쥐의 두개골에서 융비술에 사용되는 수종의 이식재에 대한 조직학적 연구
A Histological Study On Several Implants For Augmentation Rhinoplasty In Mouse Calvarium
김현섭, 박홍주, 국민석, 오희균, 김형석,
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김현섭 ( Kim Hyun-Syeob ) - 전남대학교 치의학전문대학원 구강악안면외과학교실
박홍주 ( Park Hong-Ju ) - 전남대학교 치의학전문대학원 구강악안면외과학교실
국민석 ( Kook Min-Suk ) - 전남대학교 치의학전문대학원 구강악안면외과학교실
오희균 ( Oh Hee-Kyun ) - 전남대학교 치의학전문대학원 BK21사업단
김형석 ( Kim Hyung-Seok ) - 전남대학교화순병원 병리과
KMID : 0360120070290040289
Abstract
Purpose: This study was aimed to histologically evaluate Silicone(R), Gore-tex(R), AlloDerm(R), and Medpor(R) implants for augmentation rhinoplasty after graft in the subperiosteum of mural calvarium respectively.
Material and Methods : Twenty four male ICR mice were used. Silicone(R), Gore-tex(R), AlloDerm(R), and Medpor(R) were grafted respectively in the subperiosteum of frontal bone. Animals were sacrificed at 1 week, 4 week and 8 week after graft. Histological observation was performed after HandE staining.
Results: All groups were healed without any extrusion of implant materials and inflammatory cell infiltration. In Silicone group, Silicone(R) was well enclosed by thin fibrous tissue at 1 week, which became thicker and stable at 4 weeks and 8 weeks. And there was no destruction or resorption of Silicone(R) In Gore-tex group, there was no destruction or resorption of Gore-tex(R). Thin fibrous tissue and cell infiltration from peripheral tissue were observed at 1 week, 4 weeks and 8 weeks. In AlloDerm group, AlloDerm(R) was enclosed by fibrous tissue. Cell infiltration was observed at 1 week, 4 weeks and 8 weeks. In Medpor group, there was no inflammation, destruction or resorption of Medpor(R) and it was contacted directly to the bone without interposition of fibrous tissue. Porous area was filled by bone or soft tissue.
Conclusion: These results suggest that Gore-tex(R), AlloDerm(R), and Medpor(R) graft are more stable than Silicone(R) graft and that Silicone(R), Gore-tex(R), AlloDerm(R) are appropriate for graft on nasal tip and Medpor(R) is appropriate for graft on nasal dorsum.
키워드
Graft material;Augmentation rhinoplasty
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